What does the concept of the stem cell niche really ... - BioMed Central 2012年3月9日 - The varied growth factors and cell surface molecules produced by niche cells may share the common goal of controlling stem cell pools.
An Introduction to the Stem Cell Niche: What is it, Really? 2012年3月16日 - Stem cell populations in the body live in stem cell niches, each different type of stem cell with its own niche. The niche supplies the necessary ...
Germline stem cell niches | StemBook Germline stem cells (GSCs) can generate haploid gametes, sperms or oocyte, which are responsible for transmitting genetic information from generation to generation. Because GSCs can be easily identified and gene functions can be readily manipulated in Dro
Arteriolar niches maintain haematopoietic stem cell quiescence : Nature : Nature Publishing Group a, Whole-mount immunostaining with anti-Ki-67 antibody of sterna from Nes–GFP mice. Scale bars, 50 μ m. b, Quantitative PCR analyses of Nes peri, Nes retic and CD45 − Ter119 − CD31 − Nes–GFP − stromal cells. n = 5 independent experiments. c, d, Cell ...
Fibrogenesis & Tissue Repair | Full text | Lung epithelial stem cells and their niches: Fgf10 takes Throughout life adult animals crucially depend on stem cell populations to maintain and repair their tissues to ensure life-long organ function. Stem cells are characterized by their capacity to extensively self-renew and give rise to one or more differen
Engineering microenvironments to control stem cell fate and function | StemBook Stem cell fate decisions are mediated by interactions with the matrix proteins, soluble factors and other cell types in stem cell niches. In particular, this chapter focuses on mechanisms by which niche components direct stem cell fate decisions, includin
Stem cell delivery systems inspired by tissue-specific niches Fig. 2. Designing a delivery system to regulate stem cell fate. Various cues inspired from stem cell niches play a key role in stem cell delivery systems (SCDSs). Elasticity: (A) Paxillin-labeled adhesions grow from undetectable diffuse “contacts” on neur
Emerging interactions between skin stem cells and their niches : Nature Medicine : Nature Publishing The skin protects mammals from insults, infection and dehydration and enables thermoregulation and sensory perception. Various skin-resident cells carry out these diverse functions. Constant turnover of cells and healing upon injury necessitate multiple r
Bone-marrow haematopoietic-stem-cell niches : Article : Nature ... Adult stem cells are present in most self-renewing tissues, including the skin, the intestinal epithelium and the ...
